Gel Electrophoresis Reagents and Buffers
ABclonal Technology HDAC9 Rabbit pAb
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.
ABclonal Technology ZNF23 Rabbit pAb
Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus.
ABclonal Technology ZMAT2 Rabbit pAb
Predicted to enable DNA binding activity and zinc ion binding activity. Involved in mRNA splicing, via spliceosome. Located in nucleus. Part of U2-type precatalytic spliceosome.
ABclonal Technology CDK5R1 Rabbit pAb
The protein encoded by this gene (p35) is a neuron-specific activator of cyclin-dependent kinase 5 (CDK5), the activation of CDK5 is required for proper development of the central nervous system. The p35 form of this protein is proteolytically cleaved by calpain, generating a p25 form. The cleavage of p35 into p25 results in relocalization of the protein from the cell periphery to nuclear and perinuclear regions. P25 deregulates CDK5 activity by prolonging its activation and changing its cellular location. The p25 form accumulates in the brain neurons of patients with Alzheimers disease. This accumulation correlates with an increase in CDK5 kinase activity, and may lead to aberrantly phosphorylated forms of the microtubule-associated protein tau, which contributes to Alzheimers disease.
IMCS Rapid Hydrolysis Buffer, 100mL
Rapid Hydrolysis Buffer is filter sterilized and designed to maintain optimal pH for efficient hydrolysis of IMCSzyme E1F, E1FG and 3S products.
Biophoretics Inc SERVALYT 9-11 Carrier Ampholytes, 10 mL, 40% aqueous concentrate, pH range 9-11, analytical grade, IEF, cIEF, free-flow electrophoresis
SERVALYT 9-11 Carrier Ampholytes, 10 mL, 40% aqueous concentrate, pH range 9-11, analytical grade, IEF, cIEF, free-flow electrophoresis
ABclonal Technology HTRA3 Rabbit pAb
Enables endopeptidase activity, identical protein binding activity, and serine-type peptidase activity. Involved in proteolysis. Predicted to be located in extracellular region.
ABclonal Technology FARSB Rabbit pAb
This gene encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer is responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA. A pseudogene located on chromosome 10 has been identified. Alternative splicing results in multiple transcript variants.
ABclonal Technology TAS2R10 Rabbit pAb
This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.
Perkin Elmer US LLC 2500 Run Kit for High Pressure 100 mL, 100 Bar Digestion Vessels
Includes: 10 Pressure Seals (N3133023) 7 Rupture Discs (N3133022) 50 PEEK Ring Nuts (N3133011) 5 Lip Seal Rings of the Gas Containment Manifold (N3134000)
S2 Media 15x100mm Chameleon™ COLOREX™ ESBL (RUO), 10/pack
Chameleon™ COLOREX™ ESBL (RUO) is a selective and differential, chromogenic culture medium used for the qualitative direct detection of gastrointestinal colonization with Extended-Spectrum-Beta-Lactamase (ESBL) resistant Enterobacteria. Test specimens include rectal swabs and stools. For Research Use Only (RUO). Not for use in diagnostic procedures unless Laboratory Developed Test (LDT) validation with the product has been completed. Further identification, susceptibility testing, and epidemiological typing should be performed on suspect colonies.• Product meets CLSI performance criteria.• Chameleon™ COLOREX™ ESBL should be used by trained professionals within a laboratory setting. • For in vitro diagnostic (IVD) use.• Product is not intended for use in the diagnosis or treatment of disease or other human conditions.
ABclonal Technology CHRNA7 Rabbit pAb
The nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels involved in fast synaptic signaling. These receptors are typically hetero-pentamers of homologous subunits, with each subunit containing a conserved extracellular N-terminal domain, three transmembrane domains, a variable cytoplasmic loop, a fourth transmembrane domain, and a short C-terminal extracellular region. The protein encoded by this gene forms a homo-oligomeric channel that is permeable to calcium ions and is a major component of brain nicotinic receptors. This receptor, sensitive to alpha-bungarotoxin, opens upon acetylcholine binding. This gene is linked to juvenile myoclonic epilepsy and schizophrenia. A partial duplication event in this region forms a hybrid gene with the novel FAM7A gene. Alternative splicing results in multiple transcript variants.